After 4 weeks of receiving praziquantel, 95% of these patients stopped passing schistosomal eggs in the stool. Myrrh might decrease blood sugar. Myrrh also has a potential role in the treatment of schistosomiasis and fascioliasis; however, there is limited clinical information to support these uses. This study concluded that the Mirazid formulation of myrrh has demonstrated efficacy as a fasciolicidal and schistosomicidal agent. Taking myrrh might decrease how well warfarin (Coumadin) works to slow blood clotting. It is also used as a stimulant and to increase menstrual flow. 86. A laboratory study published in Letters in Applied Microbiology in 2012 found that a combination of myrrh essential oil and frankincense essential oil may … Do not dilute the tincture. View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: (check all that apply), What factors are most important to you? It was commonly included in mixtures used to treat worms, wounds, and sepsis during the 4th century BC.4 Myrrh has also been reported to treat gout, headache, jaundice, throat ailments, indigestion, fatigue, and paralysis.5 Myrrh has been used in a variety of infectious diseases, including leprosy and syphilis, and to treat cancers.2 The Chinese have used myrrh in the management of a variety of skin and mouth infections.4 During the 10th century, myrrh was recommended to protect against plagues when travelling in endemic areas.4 It was also believed by the Greeks and Romans to be effective in the treatment of snake bites and is still used in parts of East Africa today for this indication.4 Myrrh was one of the first treatments of cough in children.4 Additionally, myrrh was incorporated as part of the mummification and cremation processes.4 Lotions containing myrrh have been made for use as cleansing agents, moisturizers, skin lesion treatments, and fragrances.5 Myrrh played a key role in the religious ceremonies of the ancient Egyptians.6 In the Bible, myrrh is cited as one of the 3 gifts (in addition to gold and frankincense) presented to Jesus by the Magi following his birth (Matthew 2:11) and was offered in a mixture of wine to Jesus during his crucifixion as an anesthetic (Mark 15:23).4 These gifts were a sign of wealth because they were rare and expensive.5 Myrrh is also a part of African, Middle Eastern, and Chinese traditional medicine. Myrrh may be an inducer of the hepatic enzymes responsible for warfarin's metabolism, though the exact mechanism is unknown. Local anesthetic activity was also noted in mammalian nerve cells.11, In a case report, a 65-year-old man with diabetes had a wound on his right foot with tissue loss. IL-4 levels were not significantly different prior to treatment with myrrh (P = 0.58; 0.72, respectively) but increased significantly following treatment for patients with fascioliasis and schistosomiasis (P = 0.04; 0.02, respectively). View abstract. Keep in mind that natural products are not always necessarily safe and dosages can be important. Commiphora mukul, a related species, is not a source of myrrh. Levels were compared to those of rats treated with phenformin whose blood glucose levels at baseline averaged 15.1 mmol/L and averaged 10.7 mmol/L following treatment. al-Harbi MM, Qureshi S, Raza M, et al. al-Harbi MM, Qureshi S, Raza M, et al. Typically, coconut, jojoba and olive oil are used as carrier oils. A disease caused by parasitic worms (schistosomiasis). All participants were given a formulation of myrrh at a dose of 12 mg/kg/day for 6 consecutive days on an empty stomach in the morning. Myrrh oil can also be made at home with myrrh … Available for Android and iOS devices. Myrrh has long been used in parts of Asia as a traditional medicine for inflammatory diseases. WebMD does not provide medical advice, diagnosis or treatment. An earlier rat study used myrrh extract (from Commiphora opobalsamum). All patients and controls received a formulation of myrrh at a dose of 10 mg/kg/day for 3 consecutive days on a empty stomach 1 hour before breakfast. Barakat R, Elmorshedy H, Fenwick A. Efficacy of myrrh in the treatment of human Schistosomiasis mansoni. Parasite reductions were noted in 2 of 6 groups (27% and 19%) who received myrrh powder and Mirazid capsules, respectively, at doses of 1,250 mg/kg. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Eighty days after study initiation, the percentage of reduction in worm burden was 30%, 65%, 77%, and 98%, respectively, for the mice in the treatment subgroups compared with mice in group 2. This could increase the chance of blood clotting. This makes it a great aid in mouth ulcers, tooth problems, and other oral issues. View abstract. © 2005 - 2019 WebMD LLC. Monitor your blood sugar closely. Four weeks following treatment, 91% of patients with fascioliasis and 100% of patients with schistosomiasis who received Mirazid experienced a parasitologic cure. Taking myrrh does not cure this infection in most children and adults. Myrrh may be of interest in the management of diabetes mellitus, although further clinical studies are necessary.25. Like frankincense, it is the sap from a myrrh tree, dried into a gum resin. Warfarin (Coumadin) is used to slow blood clotting. A sexually transmitted infection caused by Trichomonas vaginalis (trichomoniasis). Additionally, a paste containing 800 mg of bee propolis and 50 g of myrrh mixed in honey was applied topically to the wound. Evid Based Complement Alternat Med 2015;2015:925432. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. The infected patients were divided into 1 of 2 groups: those with schistosomal colitis or those with compensated or decompensated hepatosplenic schistosomiasis. The French and British continue to use myrrh in mixtures for the treatment of cough and in suppository form to treat proctitis.4, Myrrh is an oleo-gum-resin obtained from the stem of C. molmol3, 4 that consists of 2% to 10% of a volatile oil composed predominantly of sesquiterpenes, sterols, and steroids. Oncol Lett 2013;6(4):1140-6. Myrrh (pronounced "mur") is an expensive spice, used for making perfume, incense, medicine, and for anointing the dead. Tegumental histoligical effects of Mirazid and myrrh volatile oil on adult Fasciola gigantica. Am J trop Med Hyg 2005 Aug;73(2):365-7. Patients with liver dysfunction experienced a lower cure rate, but it was not statistically significant. At this time there is not enough scientific information to determine an appropriate range of doses for myrrh. The observed cure rate may be considered to be false because of a reported cure rate of 27% in the control group, although the patients reported that they had not received any antischistosomal drugs. For those with moderate infections, the cure rates were 0% for Mirazid -treated patients, 71% for praziquantel-treated patients, and 0% for control patients (P < 0.01). What factors influenced or will influence your purchase? Multiple times, Myrrh has been mentioned in the Bible as it was one of the gifts given by the tree wise men who visited Jesus.The other gifts included Gold, which symbolizes kingship, and Frankincense, which symbolizes worship. Myrrh has also been used for hemorrhoids, possibly due to its anti-inflammatory properties. The Balsamodendron myrrha, which produces the myrrh of commerce, has a wood and bark which emit a strong odor; the gum which exudes from the bark is at first oily, but becomes hard by exposure to the air. Baral S, Cho DH, Pariyar R, et al. The wound was cleaned daily followed by application of the paste. The most common adverse reactions were giddiness, somnolence, mild fatigue, and abdominal pain.20, A study was conducted to assess the efficacy of Mirazid compared with praziquantel in 459 children between 12 and 18 years of age and 672 household contacts. turmeric, saw palmetto, Ginkgo Biloba, garlic, echinacea. This study suggested that myrrh extract may have a role as an antischistosomal agent.15, In a multicenter investigation, mice and hamsters were infected with various strains of S. mansoni. It is myrrh essential oil, diluted in or blended with a carrier oil. The cure rate for subjects treated with myrrh was 16% after the first treatment compared with 74% of those treated with praziquantel ( P < 0.05). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dolara P, Corte B, Ghelardini C, et al. Composition and potential anticancer activities of essential oils obtained from myrrh and frankincense. Patients did not experience any adverse drug reactions. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Like Frankincense, myrrh has also been used for arthritis. Myrrh oil is very famous for its soothing properties, anti-depressant and uplifting spirit. 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